ULTRASOUND OF PARVOVIRUS B19 INFECTION 

  • Nonimmune fetal hydrops.
    • Subcutaneous edema.
    • Ascites.
    • Pleural and pericardial effusions.
    • May resolve spontaneously with good outcome (1).
  • Polyhydramnios (2).
  • Myocarditis / Cardiomyopathy / Pericarditis.
  • Thick placenta (due to the hydrops).
  • No structural fetal anomalies. It appears that the frequency of congenital malformation after infection is not increased as compared with the general population (1).
  • Hepatic fibrosis and necrosis (either due to direct effect on hepatocytes or indirect damage from hemosiderin deposition in hepatocytes (3).
  • Symmetric IUGR (2). The fetal growth appears to catch up once the hydrops resolves (4).
  • Assessment of the degree of fetal anemia – MC- PSV.

 

 

 

Parvovirus - Perimyocarditis

Parvovirus - Placentomegaly

Parvovirus – Pleural effusions and anasarca

Parvovirus - Hydrops

Parvovirus – Reverse diastolic flow in the umbilical artery

 

 

 

REFERENCES
  1. Torok TJ, Wang Q-Y, Gary GW Jr et.al. Prenatal diagnosis of intrauterine infection with parvovirus B19 by the polymerase chain reaction technique. Clin Infect Dis 1992;14:149-155.
  2. Bhal PS, Davies NJ, Westmoreland D et.al. Spontaneous resolution of non-immune hydrops fetalis secondary to transplacental parvovirus B19 infection. Ultrasound Obstet Gynecol 1996;7:55-57.
  3. Kilham L, Margolis G. Problems of human concern arising from animal models of intrauterine and neonatal infections due to viruses. Prog Med Virol 1975;20:113.
  4. Pryde PG, Nugent CE, Pridjian G et.al. Spontaneous resolution of non-immune hydrops secondary to parvovirus B19 infection. Obstet Gynecol 1992;79:859-861.